Polyhydroxylated Steroidal Glycosides from Paris polyphylla
Polyhydroxylated Steroidal Glycosides from Paris polyphylla
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DOI：
10.1021/np300045g
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发表时间：
2012-06-01
影响因子：
5.1
通讯作者：
Ma, Bai-Ping
中科院分区：
文献类型：
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作者：
Kang, Li-Ping;Liu, Yi-Xun;Ma, Bai-Ping
从巴黎Polyphylla Smith var.的根茎中分离得到三个新的甾体皂苷：parisyunnanosides G-I（1-3），一个新的C-21甾体苷：parisyunnanosides J（4）和三个已知化合物：padelaoside B（5），pinnatasterone（6）和20-hydroxyecdyson（7）。云南种。化合物1和3具有包括C-21 β-D-吡喃半乳糖部分的独特的三桥糖苷结构。评价了所有化合物对人CCRF白血病细胞的细胞毒性。
Three new steroidal saponins, parisyunnanosides G-I (1-3), one new C-21 steroidal glycoside, parisyunnanoside J (4), and three known compounds, padelaoside B (5), pinnatasterone (6), and 20-hydroxyecdyson (7), were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Compounds 1 and 3 have unique trisdesmoside structures that include a C-21 beta-D-galactopyranose moiety. All compounds were evaluated for their cytotoxicity against human CCRF leukemia cells.