Khat use in people living with HIV: a facility-based cross-sectional survey from South West Ethiopia
Khat use in people living with HIV: a facility-based cross-sectional survey from South West Ethiopia
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DOI：
10.1186/s12888-015-0446-5
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发表时间：
2015-04-03
期刊：
影响因子：
4.4
通讯作者：
Hanlon, Charlotte
中科院分区：
文献类型：
--
作者：
Soboka, Matiwos;Tesfaye, Markos;Hanlon, Charlotte
背景：阿拉伯茶是一种常绿植物，叶子含有苯丙胺类化合物卡西酮和去甲碱。非洲之角的许多人经常使用卡塔叶。人们已经描述了使用阿拉伯茶对健康和社会造成的不良后果，但对于埃塞俄比亚人类免疫缺陷病毒 (PLHIV) 感染者使用阿拉伯茶的情况知之甚少。本研究旨在评估在埃塞俄比亚西南部一家医院接触艾滋病毒服务的 PLHIV 中使用阿拉伯茶的流行情况以及与使用阿拉伯茶相关的因素。方法：对 2012 年 9 月在吉马大学专科医院接受艾滋病毒服务的 389 名艾滋病毒感染者进行了一项横断面研究。使用翻译成当地语言的结构化调查问卷来询问该患者群体使用阿拉伯茶的频率以及使用阿拉伯茶的潜在风险因素和后果。采用Logistic回归分析进行双变量和多变量分析。结果：目前艾滋病毒感染者中阿拉伯茶使用的总体流行率为23.0%。女性患病率为18.3%，男性患病率为33.6%。与穆斯林相比，基督徒使用阿拉伯茶的可能性较小（调整后优势比 (aOR) 0.26，95% CI = 0.13，0.55）。使用阿拉伯茶与精神困扰（aOR 1.84，95% CI = 1.01, 3.36）、吸烟（aOR 21.21，95% CI = 7.19, 62.51）、酒精使用障碍（aOR 2.16，95% CI = 1.10, 4.21）、CD4 计数之间呈正相关
Background: Khat is an evergreen plant with leaves containing the amphetamine-like compounds cathinone and cathine. Many people in the Horn of Africa use khat on a regular basis. Adverse health and social consequences of khat use have been described but little is known about the use of khat in people living with Human Immunodeficiency Virus (PLHIV) in Ethiopia. This study aimed to assess the prevalence of khat use and factors associated with khat use among PLHIV who are in contact with HIV services in a hospital in south-west Ethiopia.Methods: A cross-sectional study was conducted among 389 PLHIV who attended HIV services at Jimma University Specialized Hospital in September 2012. A structured questionnaire, translated into the local languages, was used to ask about the frequency of khat use and potential risk factors and consequences of khat use in this patient group. Logistic regression analysis was used for bivariate and multivariable analysis.Results: The overall prevalence of current khat use among people living with HIV was 23.0%. The prevalence was 18.3% in females and 33.6% in males. Christians were less likely to use khat when compared to Muslims (adjusted Odds Ratio (aOR) 0.26, 95% CI = 0.13, 0.55). There was a positive association between khat use and mental distress (aOR 1.84, 95% CI = 1.01, 3.36), smoking cigarettes (aOR 21.21, 95% CI = 7.19, 62.51), alcohol use disorders (aOR 2.16, 95% CI = 1.10, 4.21), CD4 count