Capacitation of mammalian spermatozoa.

Capacitation of mammalian spermatozoa.
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哺乳动物精子获能。

DOI:
10.1007/978-1-4684-2892-6_1
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发表时间:
1974
期刊:
Basic life sciences
影响因子:
--
通讯作者:
C. Barros
C. Barros
中科院分区:
--
文献类型:
--
作者:
C. Barros

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Austin(1951)和Chang(1951)首先认识到哺乳动物精子在雌性生殖道中发生生理变化是受精的先决条件,并将这种变化称为“获能”(Austin,1952)。他们发现,如果在排卵前将附睾或射出的精子引入雌性兔子的输卵管,卵子就会受精。然而,当精子在排卵后被引入雌性体内时,几乎没有卵子受精。换句话说,在精子获能之前,卵子就失去了受精的能力。
The need for a physiological change in mammalian spermatozoa in the female genital tract as a prerequisite for fertilization was first recognized by Austin (1951) and Chang (1951) in the rabbit, and the change was termed “capacita­tion” (Austin, 1952). They found that if epididymal or ejaculated spermatozoa were introduced into the oviduct of the female rabbit before ovulation, eggs were fertilized. However, when the spermatozoa were introduced into the female after ovulation, few-if any-eggs were fertilized. In other words, the eggs lost the ability to be fertilized before the spermatozoa became capacitated.