The usefulness of listening social media for pharmacovigilance purposes: a systematic review
The usefulness of listening social media for pharmacovigilance purposes: a systematic review
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DOI：
10.1080/14740338.2018.1531847
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发表时间：
2018-11-02
影响因子：
3.1
通讯作者：
Tuccori, Marco
中科院分区：
文献类型：
--
作者：
Convertino, Irma;Ferraro, Sara;Tuccori, Marco
引言：社交媒体挖掘可能是检索药物安全信息的一种可能策略。社交媒体的挖掘是一个不断演进的复杂过程，可分为三类：倾听（安全数据报告）、参与（跟进）和广播（风险沟通）。本系统综述旨在通过社交媒体聆听评估原始信号的有用性和质量。根据MOOSE和PRISMA声明进行的系统检索中，我们选择了2017年12月31日之前在MEDLINE、EMBASE和谷歌Scholar上发表的研究，这些研究至少听取了一个社交媒体来识别原始不良药物事件和原始信号。专家意见：选定的38项研究确定了与自发报告数据库相比信息质量较差的严重和意外的原始药物不良事件。这个特征很少允许对因果关系进行评估。只有六项研究表明，通过社交媒体收听识别的原始信号具有预测预先指定的已知信号的潜力。此外，在社交媒体上报告的患者的个人看法可以用来实施有效的风险沟通策略。然而，由于后勤和技术问题，目前不建议将社交媒体中的信号检测用于常规药物警戒。
Introduction: Social media mining could be a possible strategy to retrieve drug safety information. The mining of social media is a complex process under progressive evolution, falling into three broad categories: listening (safety data reporting), engaging (follow-up), and broadcasting (risk communication). This systematic review is aimed at evaluating the usefulness and quality of proto-signals by social media listening. Areas covered: In this systematic search, performed according to MOOSE and PRISMA statements, we selected studies, published in MEDLINE, EMBASE, and Google Scholar until 31 December 2017, that listened at least one social media to identify proto-adverse drug events and proto-signals. Expert opinion: The selected 38 studies identified serious and unexpected proto-adverse drug events characterized by poorer information quality as compared with spontaneous reporting databases. This feature allows rarely the evaluation of causal relationships. Proto-signals identified by social media listening had the potential of anticipating pre-specified known signals in only six studies. Moreover, the personal perception of patients reported in social media could be used to implement effective risk communication strategies. However, signal detection in social media cannot be currently recommended for routine pharmacovigilance, due to logistic and technical issues.