Long polar fimbriae contribute to colonization by Escherichia coli O157:H7 in vivo

Long polar fimbriae contribute to colonization by Escherichia coli O157:H7 in vivo
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DOI:
10.1128/iai.72.10.6168-6171.2004
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发表时间:
2004-10-01
影响因子:
3.1
通讯作者:
Moon, HW
Moon, HW
中科院分区:
医学2区
文献类型:
--
作者:
Jordan, DM;Cornick, N;Moon, HW

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在绵羊、普通猪和无菌仔猪中评价了长极菌毛对大肠杆菌O157:H7肠道定殖的贡献。E.大肠杆菌O157:H7菌株与lpfA1和lpfA2突变的回收率显着较低,并引起较少的附着和消失病变比亲株。
The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.