Hysterectomy with preservation of both ovaries does not result in premature ovarian failure
Hysterectomy with preservation of both ovaries does not result in premature ovarian failure
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DOI：
10.1177/147323000703500317
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发表时间：
2007-05-01
影响因子：
1.6
通讯作者：
Muhcu, M.
中科院分区：
文献类型：
--
作者：
Atay, V.;Ceyhan, T.;Muhcu, M.
本研究旨在探讨保留双侧卵巢的腹式全子宫切除术后卵巢功能和附件病理学变化，并与对照组进行比较。回顾性分析了29例40岁时行腹式全子宫切除术的患者和42例既往无卵巢病变的绝经患者的数据。经腹全子宫切除术组的平均绝经年龄（+/- SD）为49.7 +/- 1.5岁，对照组为50.1 +/- 1.3岁;该差异无统计学意义。子宫全切组囊肿和输卵管积水的发生率分别为31%和6.9%，对照组分别为44.8%和0%。经腹全子宫切除术组囊肿发生率增加有统计学意义。总之，行腹式全子宫切除术而不行卵巢切除术的患者不会发生过早绝经。保留卵巢可以避免激素替代疗法的缺点，但代价是发生附件病变的风险更高。
This study investigated ovarian function and adnexial pathology following total abdominal hysterectomy with preservation of both ovaries compared with that in a control group. Data from 29 patients who had undergone total abdominal hysterectomy at age : 40 years and 42 menopausal patients with no previous ovarian pathology were evaluated retrospectively. The mean (+/- SD) age of menopause was 49.7 +/- 1.5 years in the total abdominal hysterectomy group and 50.1 +/- 1.3 years in the control group; this difference was not statistically significant. The incidences of cyst and hydrosalpinx were 31% and 6.9%, respectively, in the total abdominal hysterectomy group and 44.8% and 0%, respectively, in the control group. The increased incidence of cysts in the total abdominal hysterectomy group was statistically significant. In conclusion, patients who undergo total abdominal hysterectomy without oophorectomy do not experience premature menopause. Preservation of the ovaries may avoid the disadvantages of hormone replacement therapy at the expense of a higher risk of developing adnexial pathology.