Use of ventriculoperitoneal shunts to treat uncontrollable intracranial hypertension in patients who have cryptococcal meningitis without hydrocephalus
Use of ventriculoperitoneal shunts to treat uncontrollable intracranial hypertension in patients who have cryptococcal meningitis without hydrocephalus
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DOI：
10.1086/340525
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发表时间：
2002-06-15
影响因子：
11.8
通讯作者：
Lu, CH
中科院分区：
文献类型：
--
作者：
Liliang, PC;Liang, CL;Lu, CH
1997年至2000年间，本院有4例人类免疫缺陷病毒阴性的隐球菌性脑膜炎伴无法控制的颅内高压。所有4例患者均接受抗真菌药物治疗和脑室-腹膜（VP）分流术治疗颅内高压。对药物治疗无反应的神经功能缺损通过使用VP分流器得以解决。隐球菌性脑膜炎引起的无法控制的颅内压升高可以通过VP分流术来解决，即使影像学检查没有显示脑积水。
Between 1997 and 2000, 4 human immunodeficiency virus-negative patients in our institution had cryptococcal meningitis with uncontrollable intracranial hypertension. All 4 patients were treated with antifungal drugs as well as ventriculoperitoneal (VP) shunts for intracranial hypertension. Neurological deficits that were unresponsive to pharmacologic treatment were resolved by use of the VP shunt. Uncontrollable elevation of intracranial pressure associated with cryptococcal meningitis can be resolved by use of a VP shunt, even when imaging studies do not reveal hydrocephalus.