Epigenetic Mechanisms Are Critical for the Regulation of WUSCHEL Expression in Floral Meristems
Epigenetic Mechanisms Are Critical for the Regulation of WUSCHEL Expression in Floral Meristems
复制标题
表观遗传机制对于花分生组织中 WUSCHEL 表达的调控至关重要
DOI：
10.1104/pp.15.00230
复制
发表时间：
2015-08-01
期刊：
影响因子：
7.4
通讯作者：
Liu, Xigang
中科院分区：
文献类型：
--
作者：
Cao, Xiuwei;He, Zishan;Liu, Xigang
花分生组织（FM）是花过渡完成后从花序分生组织发育而来的，在产生一定数量的花器官后终止。这与茎尖分生组织相反，茎尖分生组织在植物的整个生命周期中都很活跃。 WUSCHEL (WUS) 编码含有同源结构域的蛋白质，在茎尖分生组织、花序分生组织、FM 建立和维持以及 FM 决定性中发挥关键作用。尽管许多基因通过调节 WUS 表达与 FM 决定性有关，但这些基因如何协调调节 WUS 并最终决定 FM 命运仍不清楚。新出现的证据表明表观遗传机制，如组蛋白修饰、染色质重塑、非编码 RNA 和 DNA 甲基化，在分生组织的维持和终止中发挥着至关重要的作用。在此，总结和讨论了最近的研究结果，证明表观遗传网络在 FM 确定性背景下参与 WUS 表达的调节。
The floral meristem (FM), which develops from the inflorescence meristem upon completion of the floral transition, terminates after producing a defined number of floral organs. This is in contrast to the shoot apical meristem, which is active throughout the entire life span of plants. WUSCHEL (WUS) encodes a homeodomain-containing protein and plays a critical role in shoot apical meristem, inflorescence meristem, and FM establishment and maintenance as well as FM determinacy. Although many genes have been implicated in FM determinacy through the regulation of WUS expression, precisely how these genes are coordinated to regulate WUS and consequently dictate FM fate remains unclear. Emerging lines of evidence indicate that epigenetic mechanisms, such as histone modification, chromatin remodeling, noncoding RNAs, and DNA methylation, play vital roles in meristem maintenance and termination. Here, recent findings demonstrating the involvement of the epigenetic network in the regulation of WUS expression in the context of FM determinacy are summarized and discussed.