Salt sensitive human hypertension.
Salt sensitive human hypertension.
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DOI：
10.1080/07435809109027188
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发表时间：
1991
影响因子：
2.1
通讯作者：
M. Weinberger
中科院分区：
文献类型：
--
作者：
M. Weinberger
在人类中，血压对钠和细胞外液容量状态改变的反应存在异质性。已经使用了多种方法来表征血压的钠响应性，包括快速体积膨胀和收缩以及膳食钠操纵。在过去的15年里，我们的实验室进行的研究使我们能够以不同的方式检查血压的盐敏感性，并描述这种现象，以及定义与血压正常和高血压人群相关的神经体液，人口统计学和遗传因素。
Heterogeneity exists among humans in the responses of blood pressure to alterations in sodium and extracellular fluid volume status. A variety of approaches have been utilized to characterize sodium responsivity of blood pressure including rapid volume expansion and contraction and dietary sodium manipulation. Studies conducted in our laboratories over the past 15 years have enabled us to examine salt sensitivity of blood pressure in different ways and to characterize this phenomenon as well as to define neurohumoral, demographic and genetic factors associated with it in normotensive and hypertensive humans.