Estimation of total coronary artery flow using measurements of flow in the ascending aorta.
Estimation of total coronary artery flow using measurements of flow in the ascending aorta.
复制标题
使用升主动脉流量的测量来估计总冠状动脉流量。
DOI：
10.1002/mrm.1910320509
复制
发表时间：
1994
影响因子：
3.3
通讯作者：
Buonocore,MH
中科院分区：
文献类型：
--
作者：
Buonocore,MH
本文描述了一种使用MRI测量升主动脉血流来估计(右+左)冠状动脉总血流量的技术。这项技术是基于这样的原理，即支管中的流量等于支管开口上下测得的净流量之差。主动脉净流量是在四个或更多的轴向斜切切片上测量的，从主动脉瓣下方到舒张期冠脉开口最高位置上方。流动模型正确地解释了包含冠状动脉开口的切片中的流动测量结果。5例正常人的测量结果表明，冠状动脉总流量的标准误差约为90cc/min，占总冠脉流量的30%。潜在的临床应用包括冠状动脉血流储备的无创性测量。为了缩短检查时间，提高准确度和精密度，有必要对脉冲序列进行改进。
This paper describes a technique for estimation of total (right + left) coronary artery flow using MRI flow measurements in the ascending aorta. The technique is based on the principle that the flow in a vessel branch is equal to the difference of the net flow measured above and below the branch ostia. Aortic net flow is measured at four or more axial oblique slices from below the aortic valve to above the highest location of the coronary vessel ostia in late diastole. A flow model properly interprets the flow measurements in slices that contain the coronary ostia. Results in five normal subjects show that total coronary artery flow can be measured with a standard error of about 90 cc/min, 30% of total coronary artery flow. Potential clinical uses include noninvasive measurement of coronary flow reserve. Pulse sequence improvements are necessary to reduce examination time and improve accuracy and precision.