Surgical treatment of severe pulmonic stenosis under cardiopulmonary bypass in small dogs

Surgical treatment of severe pulmonic stenosis under cardiopulmonary bypass in small dogs
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DOI:
10.1111/j.1748-5827.2011.01163.x
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发表时间:
2012-02-01
影响因子:
1.6
通讯作者:
Uechi, M.
Uechi, M.
中科院分区:
农林科学3区
文献类型:
--
作者:
Fujiwara, M.;Harada, K.;Uechi, M.

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目的:本研究的目的是报告手术缓解犬肺动脉狭窄的长期结果。方法:研究对象为3只母犬和6只公犬,平均(+/- sd)年龄:23(+/- 25)个月,平均(+/- sd)体重:3.4 (+/- 2.1)kg,诊断为严重肺动脉狭窄和右心室肥厚,超声心动图平均术前压力梯度153 (+/- 43)mmHg。结果:在体外循环条件下,经瓣切开术(即开放肺动脉瓣合开术,加/不加生物膜补片移植术)可减轻严重肺动脉狭窄患者的压力过载。术后1 ~ 7天的压力梯度显著降低至65 (+/- 39)mmHg (P
OBJECTIVES: The aim of this study was to report the long-term outcome of the surgical palliation of pulmonic stenosis in dogs.METHODS: The subjects comprised three female and six male dogs, mean (+/- sd) age: 23 (+/- 25) months, mean (+/- sd) weight: 3.4 (+/- 2.1) kg, diagnosed with severe pulmonic stenosis and right ventricular hypertrophy, with an average preoperative pressure gradient of 153 (+/- 43) mmHg on echocardiography.RESULTS: The pressure overload with severe pulmonic stenosis was reduced by valvotomy, i.e., open pulmonary valve commissurotomy, with/without biomembrane patch grafting, under cardiopulmonary bypass. The postoperative pressure gradient at 1 to 7 days was significantly decreased to 65 (+/- 39) mmHg (P