Importance of progesterone to induction of sexual receptivity in spayed female rats
Importance of progesterone to induction of sexual receptivity in spayed female rats
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DOI：
10.3181/00379727-51-13979
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发表时间：
1942-12-01
影响因子：
--
通讯作者：
Beach, FA
中科院分区：
文献类型：
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作者：
Beach, FA
三组去势大鼠分别注射不同amts。雌激素和孕激素，以及性感受性。500 R.U. 7例中有2例雌激素产生了一定的感受性。同样的amt。在所有7只动物中，先给予0.5mg雌激素，然后给予0.5mg孕酮，导致了更高程度的感受性。100 R.U.雌激素0.5mg和孕激素0.5mg诱导7例中有6例的感受性较低。500 R.U.雌激素和1毫克孕酮导致相同的动物表现出更强烈的热行为。在所研究的动物品系中，正常强度的发情行为的产生显然涉及雌激素和孕酮的协同作用。
Three groups of spayed $ rats were injected with various amts. of estrogen and of progesterone, and sexual receptivity was measured. 500 R.U. of estrogen produced some receptivity in 2 of 7 cases. The same amt. of estrogen followed by 0.5 mg of progesterone resulted in a much higher degree of receptivity in all 7 animals. 100 R.U. of estrogen and 0.5 mg of progesterone induced a low degree of receptivity in 6 of 7 cases. 500 R.U. of estrogen and 1 mg of progesterone caused the same animals to exhibit much more intense heat behavior. In the strain of animals studied the production of estrous behavior of normal intensity evidently involves the synergistic action of estrogen and progesterone.