ISOLATION BY DISTANCE IN EQUILIBRIUM AND NONEQUILIBRIUM POPULATIONS
ISOLATION BY DISTANCE IN EQUILIBRIUM AND NONEQUILIBRIUM POPULATIONS
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DOI：
10.1111/j.1558-5646.1993.tb01215.x
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发表时间：
1993-02-01
期刊：
影响因子：
3.3
通讯作者：
SLATKIN, M
中科院分区：
文献类型：
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作者：
SLATKIN, M
结果表明，对于等位基因频率数据的一个有用的措施之间的基因流的程度对人口是M =（1/F（ST）- 1）/4，这是在平衡状态下的岛模型中的基因流的估计水平。对于DNA序列数据，如果F（ST）被N（ST）替换，则可以使用相同的公式。在扩散受限的种群中，分析理论表明，无论是平衡种群还是非平衡种群，M与地理距离之间都存在简单的关系，并且当突变率较小时，这种关系与突变率近似无关。模拟结果表明，合理的样本量，隔离的距离确实可以检测到，至少在某些情况下，非平衡模式可以区分。这种方法来分析隔离的距离是用于两个等位酶数据集，一个从海鸥和口袋地鼠。
It is shown that for allele frequency data a useful measure of the extent of gene flow between a pair of populations is M = (1/F(ST) - 1)/4, which is the estimated level of gene flow in an island model at equilibrium. For DNA sequence data, the same formula can be used if F(ST) is replaced by N(ST). In a population with restricted dispersal, analytic theory shows that there is a simple relationship between M and geographic distance in both equilibrium and non-equilibrium populations and that this relationship is approximately independent of mutation rate when the mutation rate is small. Simulation results show that with reasonable sample sizes, isolation by distance can indeed be detected and that, at least in some cases, non-equilibrium patterns can be distinguished. This approach to analyzing isolation by distance is used for two allozyme data sets, one from gulls and one from pocket gophers.