Comment on “Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function”
Comment on “Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function”
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对“甘露聚糖结合凝集素相关丝氨酸蛋白酶 (MASP)-1 对于人血清中凝集素途径激活至关重要，而替代途径功能不需要 MASP-1 和 MASP-3”的评论
DOI：
10.4049/jimmunol.1390002
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
T. Fujita
中科院分区：
文献类型：
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作者：
Minoru Takahashi;H. Sekine;Y. Endo;T. Fujita
我们对Degn等人的文章有几点担忧（[1][1]）。在这篇文章中，作者清楚地表明，在MASP-1和MASP-3中使用缺陷型人血清，MASP-1对于MASP-2的活化是必需的。我们同意这一点;但是，我们不同意以下几点
We have several concerns regarding the article by Degn et al. ([1][1]). In this article, the authors clearly showed that MASP-1 is essential for the activation of MASP-2 using deficient human serum in both MASP-1 and MASP-3. We are in agreement with this; however, we disagree with the following