Metabolites produced by an endophytic Phomosis sp. and their anti-TMV activity

Metabolites produced by an endophytic Phomosis sp. and their anti-TMV activity
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内生茎点病 sp. 产生的代谢物。

DOI：
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发表时间：
2017
期刊：
Molecules
影响因子：
4.6
通讯作者：
Qi-Jian Chen
Qi-Jian Chen
中科院分区：
化学2区
文献类型：
--
作者：
Qing-Wei Tan;Pei-Hua Fang;Jian-Cheng Ni;Fangluan Gao;Qi-Jian Chen

文献摘要

相似文献

通过对一株内生真菌（Phomopsis sp. FJBR-11）的发酵和代谢产物的分离，鉴定出6个化合物，包括dothiorelones A-C和H，以及cytosporones C和U。其中胞孢酮U对烟草花叶病毒（TMV）具有较强的抑制活性。此外，粗品和纯化的胞外多糖被证明对病毒感染具有较强的抑制作用。
The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and cytosporones C and U. Among these compounds, cytosporone U exhibited potent inhibitory activity against Tobacco mosaic virus (TMV). Moreover, the crude and a purified exopolysaccharide were proved to possess strong inhibitory effects against the virus infection.