Diffusion-weighted MR imaging of bone marrow:: Differentiation of benign versus pathologic compression fractures
Diffusion-weighted MR imaging of bone marrow:: Differentiation of benign versus pathologic compression fractures
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DOI：
10.1148/radiology.207.2.9577479
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发表时间：
1998-05-01
期刊：
影响因子：
19.7
通讯作者：
Deimling, M
中科院分区：
文献类型：
--
作者：
Baur, A;Stäbler, A;Deimling, M
目得：评估骨髓扩散加权磁共振（MR）成像鉴别良性和病理性椎体压缩fractions.MATERIALS和METHODS：30例39椎体压缩性骨折进行了检查与MR成像的有用性。对22例急性良性骨折和（或）创伤性骨折和17例病理性压缩骨折进行了稳态自由旋进序列MR弥散加权成像。所有患者均获得双平面X线片、T1加权自旋回波（SE）MR图像和短反转时间反转恢复（STIR）MR图像。所有序列的信号强度特征进行了定性和定量分析（骨髓对比度和信噪比）。结果：在扩散加权磁共振成像，所有良性椎体压缩骨折是低到等信号相邻的正常椎体。病理性压缩性骨折信号高于正常椎体。在弥散加权成像中，良性椎体骨折的骨髓对比度为阴性，而病理性椎体骨折的骨髓对比度为阳性（P <0.001）。T1WI SE和STIR成像对良性和病理性椎体压缩骨折的骨髓对比度差异无显著性（P > 0.01）。结论：MR弥散加权成像对病理性和良性椎体压缩骨折具有很好的鉴别作用。
PURPOSE: To evaluate the usefulness of diffusion-weighted magnetic resonance (MR) imaging of bone marrow for differentiating between benign and pathologic vertebral compression fractures.MATERIALS AND METHODS: Thirty patients with 39 vertebral compression fractures were examined with MR imaging. Diffusion-weighted MR imaging was performed with a steady-state free precession sequence in 22 acute benign osteoporotic and/or traumatic fractures and 17 pathologic compression fractures. Biplanar radiographs, T1-weighted spin-echo (SE) MR images, and short inversion time inversion-recovery (STIR) MR images were available for all patients. The signal intensity characteristics were analyzed qualitatively and quantitatively (bone marrow contrast ratios and signal-to-noise ratios) for all sequences.RESULTS: At diffusion-weighted MR imaging, all benign vertebral compression fractures were hypo- to isointense to adjacent normal vertebral bodies. Pathologic compression fractures were hyperintense to normal vertebral bodies. Benign vertebral fractures had negative bone marrow contrast ratios at diffusion-weighted imaging, whereas pathologic vertebral fractures had positive values (P < .001). The difference in bone marrow contrast ratios for benign and pathologic compression fractures at T1-weighted SE and STIR imaging was not significant (P > .01).CONCLUSION: Diffusion-weighted MR imaging provided excellent distinction between pathologic and benign vertebral compression fractures.