Interpretation of concentration-dependence in aggregation kinetics
Interpretation of concentration-dependence in aggregation kinetics
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DOI：
10.1016/j.bpc.2003.12.003
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发表时间：
2004-05-01
影响因子：
3.8
通讯作者：
Kodaka, M
中科院分区：
文献类型：
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作者：
Kodaka, M
用随机聚合模型和成核相关聚合模型分析了聚合过程。可以解析地推导出随机聚合模型的动力学方程，揭示了初始单体浓度([M](0))、速率常数(k(A))、时间(T)、可检测聚集体的产率([F])和临界聚集数(M)之间的关系。然而，通过数值计算可以得到与成核有关的聚合模型的时间-过程曲线。结果表明，在无规聚合模型中，滞后时间(t(D))和半衰期(t(1/2))与[M](-1)成正比，而在浓度较低时，t(D)和t(1/2)与[M-1](-1)成正比(1<；S和lt；n；n为核尺寸)，而在成核相关聚合模型中，较高浓度下t(D)和t(1/2)与[M-1]成正比。(C)2003爱思唯尔B.V.保留所有权利。
Aggregation processes are analyzed by two kinetic models, the random polymerization model and the nucleation-dependent polymerization model. A kinetic equation for the random polymerization model can be derived analytically, revealing the relation between the initial monomer concentration ([M](0)), the rate constant (k(a)), time (t), the yield of detectable aggregate ([F]), and the critical aggregation number (m). However, time-course curves for the nucleation-dependent polymerization model can be obtained by numerical calculation. It is found that lag time (t(d)) and half-time (t(1/2)) are proportional to [M](-1) in the random polymerization model, while t(d) and t(1/2) are proportional to [M-1](-1) (1 < s < n; n is nucleus size) at the lower concentration and are less dependent on [M-1] at the higher concentration in the nucleation-dependent polymerization model. (C) 2003 Elsevier B.V. All rights reserved.