Surgery and transplantation for hepatocellular cancer
Surgery and transplantation for hepatocellular cancer
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DOI：
10.1053/jlts.2000.19010
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发表时间：
2000-11-01
影响因子：
4.6
通讯作者：
Marotta, PJ
中科院分区：
文献类型：
--
作者：
Wall, WJ;Marotta, PJ
1.肝细胞癌(HCC)的治愈取决于早期诊断。2.在没有肝硬化的情况下发生的可手术的HCC的治愈率仅为10%至25%。3．肝硬化患者肝细胞癌肝移植后5年生存率达75%的特点包括：（1）单发肿瘤小于5cm； (2)肿瘤3个或以下，每个肿瘤小于3厘米； (3) 无血管侵犯。4．晚期肝硬化限制了部分肝切除术在HCC患者中的广泛应用。5．尚未证明新辅助治疗可以改善通过移植及时治疗的早期 HCC 患者的预后。
1. Curative treatment of hepatocellular carcinoma (HCC) depends on early diagnosis.2. The cure rate for operable HCC occurring in the absence of cirrhosis is only 10% to 25%.3. Features of HCC in patients with cirrhosis that are associated with a 5-year survival rate of 75% after liver transplantation include (1) solitary tumor less than 5 cm; (2) 3 or fewer tumors, each less than 3 cm; and (3) absence of vascular invasion.4. Advanced cirrhosis limits the widespread application of partial hepatectomy to patients with HCC.5. Neoadjuvant therapy has not yet been proven to improve patient outcome for early-stage HCC that is promptly treated by transplantation.