TOPOGRAPHY AND INTRA-CRANICAL SOURCES OF SOMATOSENSORY EVOKED-POTENTIALS IN THE MONKEY .2. CORTICAL COMPONENTS
TOPOGRAPHY AND INTRA-CRANICAL SOURCES OF SOMATOSENSORY EVOKED-POTENTIALS IN THE MONKEY .2. CORTICAL COMPONENTS
复制标题
DOI：
10.1016/0013-4694(81)91505-4
复制
发表时间：
1981-01-01
期刊：
影响因子：
--
通讯作者：
LEGATT, AD
中科院分区：
文献类型：
--
作者：
AREZZO, JC;VAUGHAN, HG;LEGATT, AD
在刺激猴子的对侧中神经后，从一系列硬膜外和皮质内位置记录平均体感诱发电位（SEP）和相关的多单位活动（MUA）。将皮质成分与早期皮质下活动区分开来，并确定每个皮质电位的脑内分布和来源。在巴比妥麻醉下，SEP 波形被简化，可完全归因于 2 个来源。最早的皮质活动由中央沟后岸产生的双相 P10-N20 波组成。第二个波形 P12-N25 起源于中央后回的冠部。没有其他皮质区域处于活跃状态。在警戒状态下，表面 SEP 的形态很复杂，反映了来自多个相邻皮质源的体积传导活动的相互作用。覆盖中央后回手部区域的波形由 P12、P20、P40、N45 和 P110 组成。中央前录音显示 P10、P13、N13、N20、P24、N45 和 P110。已确定六个解剖学来源。 P10 和 N20 起源于中央沟后岸，包括区域 3a 和 3b，并且是沿前后方向进行的体积。 P12 起源于区域 1 以及区域 2 的前部。P20 产生于中央后回的内侧部分，包括区域 5。P40 的来源位于顶叶的外侧部分，包括区域 7b。中央前皮质产生两个成分：P13/N13 主要起源于中央沟前岸的区域 4，P24 反映中央前回前内侧部分（包括区域 6）的活动。长潜伏期 SEP 成分 N45 和 P110 广泛在皮质的感觉区域内产生。早期皮质 SEP 与人类的相似，但后者的潜伏期更长，反映了物种间的差异。
Averaged somatosensory evoked potentials (SEP) and associated multiple unit activity (MUA) were recorded from a series of epidural and intracortical locations following stimulation of the contralateral medium nerve in the monkey. Cortical components were differentiated from the earlier subcortical activity and the intracerebral distribution and sources of each cortical potential were determined. Under barbiturate anesthesia the SEP wave form is simplified and can be wholly attributed to 2 sources. The earliest cortical activity consists of a biphasic P10-N20 wave which is generated in the posterior bank of the central sulcus. A 2nd wave form, P12-N25, originates in the crown of the postcentral gyrus. No other cortical areas are active. In the alert state the morphology of the surface SEP is complex and reflects the interaction of volume conducted activity from several adjacent cortical sources. The wave form overlying the hand area of the postcentral gyrus consists of P12, P20, P40, N45 and P110. Precentral recordings exhibit P10, P13, N13, N20, P24, N45 and P110. Six anatomical sources have been identified. P10 and N20 originate in the posterior bank of the central sulcus including areas 3a and 3b and are volume conducted in an anteroposterior direction. P12 originates in area 1 as well as the anterior portion of area 2. P20 is generated in the medial portion of the postcentral gyrus including area 5. The source of P40 lies within the lateral portion of the parietal lobe including area 7b. Two components were generated in precentral cortex: P13/N13 originates principally in area 4 within the anterior bank of the central sulcus and P24 reflects activity in the anteromedial portion of the precentral gyrus including area 6. The long latency SEP components, N45 and P110 are generated widely within the somesthetic areas of the cortex. The early cortical SEP resemble those from man, but the latter are longer in latency, reflecting interspecies differences.