Tourniquet Use During Knee Replacement Surgery May Contribute to Muscle Atrophy in Older Adults.
Tourniquet Use During Knee Replacement Surgery May Contribute to Muscle Atrophy in Older Adults.
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DOI：
10.1249/jes.0000000000000076
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发表时间：
2016-04
影响因子：
5.7
通讯作者：
Dreyer HC
中科院分区：
文献类型：
--
作者：
Dreyer HC
Muscle atrophy after total knee arthroplasty (TKA) occurs at a rate of 1% per day for the first two weeks. Our hypothesis is that tourniquet-induced IR injury occurring during TKA influences metabolism and may contribute to atrophy. Identifying pathways that are up regulated during this critical “14-day window” after surgery may help us to delineate therapeutic approaches to avoid muscle loss.
