Design and demonstration of a miniature catheter for a confocal microendoscope
Design and demonstration of a miniature catheter for a confocal microendoscope
复制标题
DOI：
10.1364/ao.43.005763
复制
发表时间：
2004-11-01
期刊：
影响因子：
1.9
通讯作者：
Gmitro, AF
中科院分区：
文献类型：
--
作者：
Rouse, AR;Kano, A;Gmitro, AF
荧光共聚焦显微内窥镜在光学活检期间提供细胞病理的高分辨率体内成像。共聚焦显微内窥镜采用柔性光纤导管耦合到定制的狭缝扫描共聚焦显微镜。该导管由连接到微型物镜和聚焦组件的光纤成像束组成。直径为3 mm的导管可以单独使用，也可以通过市售内窥镜的器械通道使用，为传统内窥镜增加了显微成像能力。讨论了小型物镜和聚焦组件的设计和性能。该系统的主要应用包括胃肠道和女性生殖系统疾病的诊断。(C)2004年美国光学学会。
The fluorescence confocal microendoscope provides high-resolution, in vivo imaging of cellular pathology during optical biopsy. The confocal microendoseope employs a flexible fiber-optic catheter coupled to a custom-built slit-scan confocal microscope. The catheter consists of a fiber-optic imaging bundle linked to a miniature objective and focus assembly. The 3-mm-diameter catheter may be used on its own or routed though the instrument channel of a commercial endoscope, adding microscopic imaging capability to conventional endoscopy. The design and performance of the miniature objective and focus assembly are discussed. Primary applications of the system include diagnosis of disease in the gastrointestinal tract and female reproductive system. (C) 2004 Optical Society of America.