Ventilation Increases with Lower Extremity Venous Occlusion in Young Adults
Ventilation Increases with Lower Extremity Venous Occlusion in Young Adults
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DOI：
10.1249/mss.0000000000000797
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发表时间：
2016-03-01
期刊：
影响因子：
--
通讯作者：
Olson, Thomas P.
中科院分区：
文献类型：
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作者：
Keller-Ross, Manda L.;Sarkinen, Andrielle L.;Olson, Thomas P.
IntroductionVenous diffusion via subsystolic occlusion of the lower limbs may augment ventilation via stimulation of group III/IV inferred neurons.PurposeThe purpose of this study was to examinatory response to graded lower extremity venous occlusion during exercise in healthy adults.MethodsNineteen adults（9 men，25 +/- 5 yr）completed two visits.访视1包括最大踏车测力运动试验。访视2包括30%峰值工作负荷循环运动，双侧大腿压力止血带随机充气至20、40、60、80和100 mm Hg，每次2 min，间隔2 min放气。套囊前进行3分钟循环（对照[CTL]）。在每次治疗期间测量呼气分钟通气量（V-E）、全身气体交换、主观用力评分和呼吸困难。（仅限运动，CTL）到每个闭塞压力（P < 0.05），在100 mm Hg时增加最大（CTL至100 mm Hg：31.5 +/- 6.6至40.1 +/- 10.7 L中心点min（-1））。呼吸频率（R-R）也增加（CTL至100 mm Hg：24.8 +/- 6.0至30.9 +/- 11.5次呼吸/分钟，P < 0.05，条件效应），潮气量无变化（P > 0.05）。潮气量/吸气时间（V-T/T-I）从CTL条件到每个阻塞压力显著增加（CTL到100 mm Hg：1.5 +/- 0.3到1.8 +/- 0.4 L中心点min（-1），P < 0.05，所有压力）。呼吸困难和RPE增加与所有闭塞压力从CTL exercise（P < 0.05，所有的压力）。ConclusionsOur研究结果表明，轻度至中度下肢静脉闭塞引起呼吸急促的呼吸模式，这反过来又增加了V-E和运动过程中感知的呼吸努力。
IntroductionVenous distention via subsystolic occlusion of the lower limbs may augment ventilation via stimulation of group III/IV afferent neurons.PurposeThe purpose of this study was to examine the ventilatory response to graded lower extremity venous occlusion during exercise in healthy adults.MethodsNineteen adults (9 men, 25 +/- 5 yr) completed two visits. Visit 1 included a maximal cycle ergometry exercise test. Visit 2 included a 30% peak workload cycle exercise with randomized inflations of bilateral thigh pressure tourniquets to 20, 40, 60, 80, and 100 mm Hg for 2 min each, separated by 2 min of deflation. Three minutes of cycling occurred before cuffing (control [CTL]). Expired minute ventilation (V-E), whole body gas exchange, rating of perceived exertion, and dyspnea were measured during each session.ResultsV-E increased significantly from the control condition (exercise only, CTL) to each occlusion pressure (P < 0.05) with the greatest increase at 100 mm Hg (CTL to 100 mm Hg: 31.5 +/- 6.6 to 40.1 +/- 10.7 L center dot min(-1)). Respiratory rate (R-R) increased as well (CTL to 100 mm Hg: 24.8 +/- 6.0 to 30.9 +/- 11.5 breaths per minute, P < 0.05, condition effect) with no change in tidal volume (P > 0.05). Tidal volume to inspiratory time (V-T/T-I) increased significantly from the CTL condition to each occlusion pressure (CTL to 100 mm Hg: 1.5 +/- 0.3 to 1.8 +/- 0.4 L center dot min(-1), P < 0.05, all pressures). Dyspnea and RPE increased with all occlusion pressures from CTL exercise (P < 0.05, all pressures).ConclusionsOur findings suggest that mild-to-moderate venous occlusion of the lower extremity evokes a tachypneic breathing pattern which, in turn, augments V-E and perceived breathing effort during exercise.