Corrosion Behavior and In Vitro Cytotoxicity of Ni-Ti and Stainless Steel Arch Wires Exposed to Lysozyme, Ovalbumin, and Bovine Serum Albumin
Corrosion Behavior and In Vitro Cytotoxicity of Ni-Ti and Stainless Steel Arch Wires Exposed to Lysozyme, Ovalbumin, and Bovine Serum Albumin
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暴露于溶菌酶、卵清蛋白和牛血清白蛋白的镍钛和不锈钢弓丝的腐蚀行为和体外细胞毒性
DOI：
10.1021/acsomega.0c02312
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发表时间：
2020
期刊：
影响因子：
4.1
通讯作者：
Shao Longquan
中科院分区：
文献类型：
--
作者：
Zhang Chao;He Longwen;Chen Yuming;Dai Danni;Su Yuan;Shao Longquan
在这项研究中，蛋白质和机械负荷有助于腐蚀的趋势和机制，通过暴露镍钛合金和不锈钢弓丝在不同的机械负荷下含有不同类型的蛋白质（溶菌酶，卵清蛋白，牛血清白蛋白）的人工唾液。腐蚀行为和体外细胞毒性结果表明，暴露于蛋白质和机械应力显着降低不锈钢的耐腐蚀性，并增加有毒腐蚀产物的释放。添加蛋白质对Ni-Ti合金的腐蚀有抑制作用，但机械载荷的作用则相反。即使是含有相同类型氨基酸的蛋白质对同一合金的耐腐蚀性也有不同的影响。在金属医用材料的应用中，应考虑蛋白质或应力的影响，或它们的组合。
In this study, the tendency and mechanisms by which protein and mechanical loads contribute to corrosion were determined by exposing Ni–Ti and stainless steel arch wires under varying mechanical loads to artificial saliva containing different types of protein (lysozyme, ovalbumin, and bovine serum albumin). The corrosion behavior and in vitro cytotoxicity results show that exposure to both protein and mechanical stress significantly decreased the corrosion resistance of stainless steel and increased the release of toxic corrosion products. Adding protein inhibited the corrosion of Ni–Ti, but the mechanical loads counteracted this effect. Even proteins containing the same types of amino acids had different effects on the corrosion resistance of the same alloy. The effect of protein or stress, or their combination, should be considered in the application of metal medical materials.