New synthesis of unsymmetrically-substituted 2,5-diarylpyrroles from homopropargyl sulfonamides
New synthesis of unsymmetrically-substituted 2,5-diarylpyrroles from homopropargyl sulfonamides
复制标题
DOI：
10.1039/c3ra46579a
复制
发表时间：
2014-01
期刊：
影响因子：
3.9
通讯作者：
W. V. Rossom;Y. Matsushita;K. Ariga;Jonathan P. Hill
中科院分区：
文献类型：
--
作者：
W. V. Rossom;Y. Matsushita;K. Ariga;Jonathan P. Hill
以高炔丙基磺酰胺为原料，经5-端位环合和连续脱保护反应合成了2，5-二芳基吡咯。醛的逐步精制允许在吡咯环处引入各种官能芳基部分。
Unsymmetrically-substituted 2,5-diarylpyrroles were prepared by 5-endo-dig cyclization with consecutive deprotection of homopropargyl sulfonamides. Stepwise elaboration of an aldehyde allows the introduction of a variety of functional aryl moieties at the pyrrole ring.