Hyperpolarization induces a rise in intracellular sodium concentration in dopamine cells of the substantia nigra pars compacta

Hyperpolarization induces a rise in intracellular sodium concentration in dopamine cells of the substantia nigra pars compacta
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超极化导致黑质致密部多巴胺细胞内钠离子浓度升高

DOI:
10.1046/j.1460-9568.1998.00195.x
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发表时间:
1998
影响因子:
3.4
通讯作者:
N. Mercuri
N. Mercuri
中科院分区:
医学3区
文献类型:
--
作者:
T. Knöpfel;E. Guatteo;G. Bernardi;N. Mercuri

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我们研究了大鼠中脑切片制备中膜电压变化对黑质背侧部多巴胺敏感神经元细胞内钠浓度([Na+]i)的影响。将全细胞膜片钳技术与使用Na+敏感探针钠结合苯并呋喃三乙酸酯(SBFI)的[Na+]i显微荧光测量相结合。自发超极化
We investigated the effect of changes in membrane‐voltage on intracellular sodium concentration ([Na+]i) of dopamine‐sensitive neurons of the substantia nigra pars compacta in a slice preparation of rat mesencephalon. Whole‐cell patch‐clamp techniques were combined with microfluorometric measurements of [Na+]i using the Na+‐sensitive probe, sodium‐binding benzofuran isophthalate (SBFI). Hyperpolarization of spontaneously
DOI: 10.1016/s0021-9258(19)47321-3
发表时间: 1989-11
期刊: The Journal of biological chemistry
影响因子: --
作者:
Akwasi MintaS;Roger Y. TsienO
通讯作者: Akwasi MintaS;Roger Y. TsienO