EXPERIMENTAL INCLUSION CONJUNCTIVITIS IN MAN .3. KERATITIS AND OTHER COMPLICATIONS

EXPERIMENTAL INCLUSION CONJUNCTIVITIS IN MAN .3. KERATITIS AND OTHER COMPLICATIONS
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DOI:
10.1001/archopht.1967.00980030343015
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发表时间:
1967-01-01
影响因子:
--
通讯作者:
HANNA, L
HANNA, L
中科院分区:
其他
文献类型:
--
作者:
DAWSON, C;WOOD, TR;HANNA, L

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感染包涵性结膜炎剂的志愿者除急性滤泡性结膜炎外,还经常发生角膜炎。角膜征象包括上皮性角膜炎,边缘和中央上皮下浸润,角膜边缘局灶性新生血管形成。在再次感染的志愿者中,角膜炎并不比初次感染更频繁,但出现得更快。3例患者在实验感染过程中出现前葡萄膜炎。在2名志愿者中,这种情况与结膜疾病的复发同时发生。虽然成人经典沙眼和包涵性结膜炎的临床症状有相当多的重叠,但仍应将两者视为不同的临床实体。
Volunteers infected with inclusion conjunctivitis agent regularly developed keratitis in addition to acute follicular conjunctivitis. The corneal signs included epithelial keratitis, marginal and central subepithelial infiltrates, and focal neovasculari-zation at the limbus. In reinfected volunteers, keratitis was no more frequent but appeared sooner than in initial infections. In 3 instances, anterior uveitis appeared during the course of experimental infections. In 2 volunteers this occurred in conjunction with the reactivations of conjunctival disease. Although there is considerable overlapping of the clinical signs of classic trachoma and inclusion conjunctivitis in adults, the 2 diseases should still be regarded as distinct clinical entities.