Evolution and speciation of Pneumocystis.
Evolution and speciation of Pneumocystis.
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肺孢子虫的进化和物种形成。
DOI：
10.1111/j.1550-7408.2003.tb00655.x
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发表时间：
2003
期刊：
影响因子：
--
通讯作者：
Stringer,JamesR
中科院分区：
文献类型：
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作者：
Keely,ScottP;Fischer,JaredM;Stringer,JamesR
过去十年的研究表明，肺孢子虫属包含许多不同的生物体。人们观察到它们的细胞表面、生长所需的条件以及基因组存在差异。这些生物体表现出的遗传和功能多样性表明肺孢子虫包含不止一种物种。围绕这个问题存在争议，因为肺孢子虫无法培养，也无法进行交配实验。然而，几个基因直向同源物之间的序列变异程度表明，DNA 可用于诊断肺孢子虫属物种，这反过来又表明需要修改其命名法。 1976 年，Frenkel 在动物学法规下将该物种命名为 P. jirovecii [6]，并于 1999 年将其转入植物学法规 [7]，从而有效地应用了两个新物种名称：Pneumocystis jirovecii n. 和 Pneumocystis jirovecii n. 。 sp。和卡氏肺孢子虫 n. sp.，分别用于源自人类和大鼠的生物体。本文的目的是确定单个系统发育是否是多个基因谱系的基础，并估计物种形成的时间。
Studies during the last decade have revealed that the genus Pneumocystis contains many distinct organisms. Differences have been observed for their cell surfaces, the conditions required for their growth, and their genomes. The genetic and functional diversity exhibited by these organisms indicate Pneumocystis contains more than one species. Controversy surrounds this issue because Pneumocystis cannot be cultured and mating experiments cannot be performed. However, the degree of sequence variation seen between several gene orthologues suggested that DNA could be utilized to diagnose Pneumocystis species, which in turn, has indicated the need for revising its nomenclature. In 1976 Frenkel named the species in human P. jirovecii [6] under the zoological code and in 1999, he transferred it to the botanical code [7] thus validly applying two new species names, Pneumocystis jirovecii n. sp. and Pneumocystis carinii n. sp., for organisms derived from human and rat, respectively. The purpose of this article is to determine if a single phylogeny underlies the genealogies of several genes and to estimate the times of speciation.