Suicide after successful deep brain stimulation for movement disorders
Suicide after successful deep brain stimulation for movement disorders
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DOI：
10.1212/01.wnl.0000145603.48221.b5
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发表时间：
2004-12-14
期刊：
影响因子：
9.9
通讯作者：
Ghika, J
中科院分区：
文献类型：
--
作者：
Burkhard, PR;Vingerhoets, FJG;Ghika, J
作者在接受脑深部电刺激（DBS）治疗的大型运动障碍患者队列中观察到较高的自杀率（6/140例患者，4.3%）。明显的风险因素包括既往重度抑郁史和多次连续DBS手术，而与基础疾病、DBS靶点、电参数或治疗调整无关。巧合的是，所有患者在手术后都经历了极好的运动结局。作者建议，DBS手术应排除自杀风险高的患者。
The authors observed a high rate of suicide (6/140 patients, 4.3%) in a large cohort of patients with movement disorders treated with deep brain stimulation (DBS). Apparent risk factors included a previous history of severe depression and multiple successive DBS surgeries, whereas there was no relationship with the underlying condition, DBS target, electrical parameters, or modifications of treatment. Paradoxically, all patients experienced an excellent motor outcome following the procedure. The authors propose that patients at high risk for suicide should be excluded from DBS surgery.