CopyMap: localization and calling of copy number variation by joint analysis of hybridization data from multiple individuals.
CopyMap: localization and calling of copy number variation by joint analysis of hybridization data from multiple individuals.
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CopyMap：通过联合分析多个个体的杂交数据来定位和识别拷贝数变异。
DOI：
10.1093/bioinformatics/btq515
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Zollner,Sebastian
中科院分区：
文献类型：
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作者：
Zollner,Sebastian
Summary:The program package CopyMap identifies copy number variation from oligo-hybridization and CGH data. Using a time-dependent hidden Markov model to combine evidence of copy number variants (CNVs) across multiple carriers, CopyMap is substantially more accurate than standard hidden Markov methods in identifying CNVs and calling CNV-carriers. Moreover, CopyMap provides more precise estimates of CNV-boundaries.Availability:The C-source code and detailed documentation for the program CopyMap is available on the Internet at http://www.sph.umich.edu/csg/szoellner/Contact:szoellne@umich.eduSupplementary information:Supplementary data are available atBioinformaticsonline.
