Breast cancer tumor size: correlation between magnetic resonance imaging and pathology measurements
Breast cancer tumor size: correlation between magnetic resonance imaging and pathology measurements
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DOI：
10.1016/j.amjsurg.2008.07.028
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发表时间：
2008-12-01
影响因子：
3
通讯作者：
Osland, Jacqueline S.
中科院分区：
文献类型：
--
作者：
Onesti, Jill K.;Mangus, Barry E.;Osland, Jacqueline S.
背景：随着医生越来越多地使用磁共振成像(MRI)来评估新诊断的乳腺癌，有必要对MRI与病理肿瘤大小的相关性进行综述。方法：对91例乳腺肿瘤患者进行回顾性分析，将术前MRI肿瘤大小与最终病理肿瘤大小进行比较。结果：MRI与病理肿瘤大小呈正相关(R=.650)。但MRI平均高估了0.63厘米(P<；0.0001)。当按MRI肿瘤大小(2.0 cm)分层时，仅在大于2.0 cm的肿瘤中发现显著差异(平均高估=1.06 cm；P<；0.0001)。这一趋势在导管原位癌(DCIS)、浸润性导管癌(IDC)和浸润性小叶癌(ILC)的组织学亚型中持续存在。结论：MRI肿瘤的大小与病理大小相关；然而，存在明显的高估，特别是对于肿瘤>；2.0 cm。因此，临床医生在确定保乳治疗(BCT)的可行性时应谨慎依赖MRI肿瘤大小。(C)2008 Elsevier Inc.保留所有权利。
BACKGROUND: As physicians increasingly use magnetic resonance imaing (MRI) for the evaluation of newly diagnosed breast cancers, a review of the correlation between MRI and pathology tumor size is imperative.METHODS: A retrospective review of 91 breast tumors comparing preoperative MRI tumor size to final pathology tumor size was performed.RESULTS: MRI and pathology tumor size were positively correlated (R = .650). but with an average overestimation by MRI of .63 cm (P < .0001). When stratified by MRI tumor size (2.0 cm), a significant difference was found only in tumors greater than 2.0 cm (average overestimation = 1.06 cm; P < .0001). This trend continued for the histological subtypes of ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC), and invasive lobular carcinoma (ILC).CONCLUSIONS: MRI tumor size correlates with pathology size; however, a significant overestimation exists, particularly for tumors >2.0 cm. Clinicians should therefore use caution in relying on MRI tumor size in determining candidacy for breast conservation therapy (BCT). (C) 2008 Elsevier Inc. All rights reserved.