Synchronous beta rhythms of frontoparietal networks support only behaviorally relevant representations
Synchronous beta rhythms of frontoparietal networks support only behaviorally relevant representations
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DOI：
10.7554/elife.17822
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发表时间：
2016-11-14
期刊：
影响因子：
7.7
通讯作者：
Miller, Earl K.
中科院分区：
文献类型：
--
作者：
Antzoulatos, Evan G.;Miller, Earl K.
分类与灵长类大脑的分布式网络有关，包括前额叶皮层（PFC）和后顶叶皮层（PPC）。虽然PFC和PPC的类别选择性尖峰已经建立，额顶网络的频率依赖的动态相互作用在很大程度上是未知的。我们训练猴子执行延迟匹配到空间类别的任务，同时用多个电极记录来自PFC和PPC的尖峰和局部场电位。我们发现了类别选择性β-和δ-带之间和内部的区域同步。然而，除了类别，三角洲同步和尖峰活动也反映了无关的刺激尺寸。相比之下，β同步只传达了与任务相关的类别的信息。此外，类别选择性PFC神经元与PPC β振荡同步，而携带无关信息的神经元则不同步。这些结果表明，长距离β-波段同步可以作为一个过滤器，只支持与手头任务相关的变量的神经表征。
Categorization has been associated with distributed networks of the primate brain, including the prefrontal cortex (PFC) and posterior parietal cortex (PPC). Although category selective spiking in PFC and PPC has been established, the frequency-dependent dynamic interactions of frontoparietal networks are largely unexplored. We trained monkeys to perform a delayed-match-to-spatial-category task while recording spikes and local field potentials from the PFC and PPC with multiple electrodes. We found category-selective beta- and delta-band synchrony between and within the areas. However, in addition to the categories, delta synchrony and spiking activity also reflected irrelevant stimulus dimensions. By contrast, beta synchrony only conveyed information about the task-relevant categories. Further, category-selective PFC neurons were synchronized with PPC beta oscillations, while neurons that carried irrelevant information were not. These results suggest that long-range beta-band synchrony could act as a filter that only supports neural representations of the variables relevant to the task at hand.