Prevalence and correlates of sexual dysfunction among women with bladder pain syndrome/interstitial cystitis.
Prevalence and correlates of sexual dysfunction among women with bladder pain syndrome/interstitial cystitis.
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DOI：
10.1016/j.urology.2010.10.016
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发表时间：
2011-03
期刊：
影响因子：
2.1
通讯作者：
Berry SH
中科院分区：
文献类型：
--
作者：
Bogart LM;Suttorp MJ;Elliott MN;Clemens JQ;Berry SH
性功能障碍可导致膀胱疼痛综合征/间质性膀胱炎（BPS/IC）女性的生活质量降低。我们在兰德公司间质性膀胱炎流行病学研究（RICE）中，基于美国家庭的概率抽样调查，检查了女性中一般性和BPS/IC特异性功能障碍的患病率和相关性。我们致电146，231户家庭，以确定报告膀胱症状或BPS/IC诊断的妇女。那些报告的人接受了使用RICE高特异性症状标准的第二阶段筛查（骨盆区域疼痛，压力或不适;白天尿频10次以上或由于疼痛，压力或不适（不害怕弄湿）而尿急;膀胱充盈时疼痛;抗生素治疗后膀胱症状未消退;从未接受过子宫内膜异位症的激素注射治疗）。符合RICE标准的女性（n = 1，469）完成了BPS/IC特异性和一般性功能障碍症状，膀胱症状严重程度，一般身体健康，抑郁症，就医和社会人口统计学特征的测量。在目前有性伴侣的患者中（75%），88%的患者在过去4周内报告了≥1种一般性功能障碍症状，90%的患者报告了≥1种BPS/IC特异性功能障碍症状。在多变量模型中，BPS/IC特异性功能障碍与更严重的BPS/IC症状、更年轻、更严重的抑郁症状和更差的总体健康状况显著相关。一般性功能障碍的多变量相关因素包括非拉丁裔种族/民族、已婚和有抑郁症状。患有BPS/IC症状的女性经历非常高水平的性功能障碍。性功能障碍与症状相关。
Sexual dysfunction can contribute to reduced quality of life among women with bladder pain syndrome/interstitial cystitis (BPS/IC). We examined prevalence and correlates of general and BPS/IC-specific sexual dysfunction among women in the RAND Interstitial Cystitis Epidemiology Study (RICE) based on a probability sample survey of U.S. households. We telephoned 146,231 households to identify women who reported bladder symptoms or a BPS/IC diagnosis. Those who reported either were subject to a second-stage screening using RICE high-specificity symptom criteria (pain, pressure, or discomfort in pelvic area; daytime urinary frequency 10+ times or urgency due to pain, pressure, or discomfort (not fear of wetting); pain worsens as the bladder fills; bladder symptoms did not resolve after antibiotic treatment; and never treated with hormone injections for endometriosis). Women who met RICE criteria (n = 1,469) completed measures of BPS/IC-specific and general sexual dysfunction symptoms, bladder symptom severity, general physical health, depression, medical care-seeking, and socio-demographic characteristics. Of those with a current sexual partner (75%), 88% reported ≥1 general sexual dysfunction symptom and 90% reported ≥1 BPS/IC-specific sexual dysfunction symptom in the past 4 weeks. In multivariate models, BPS/IC-specific sexual dysfunction was significantly associated with more severe BPS/IC symptoms, younger age, worse depression symptoms, and worse perceived general health. Multivariate correlates of general sexual dysfunction included non-Latino race/ethnicity, being married, and having depression symptoms. Women with BPS/IC symptoms experience very high levels of sexual dysfunction. Sexual dysfunction covaries with symptoms.
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