Epidemiology of interstitial cystitis: A population based study
Epidemiology of interstitial cystitis: A population based study
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DOI：
10.1016/s0022-5347(01)61947-5
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发表时间：
1999-02-01
影响因子：
6.6
通讯作者：
Stampfer, MJ
中科院分区：
文献类型：
--
作者：
Curhan, GC;Speizer, FE;Stampfer, MJ
目的：间质性膀胱炎是一种慢性、使人衰弱的综合征，但令人惊讶的是，对其流行病学知之甚少。这项研究的目的是估计妇女间质性膀胱炎的患病率在美国。材料和方法：女性参与者在护士健康研究（NHS）I和II（184,583）被问及邮寄问卷调查是否他们曾经被诊断为间质性膀胱炎。我们要求并审查了自我报告的女性间质性膀胱炎的病历。自我报告的准确性进行了评估，使用标准化criterions.Results：在93,428名妇女谁回答了NHS II问卷和91,155名妇女谁回答了NHS I问卷1,354（1.4%）和357（0.4%），分别，自我报告间质性膀胱炎。根据病历审查，NHS II和NHS I分别确认了63例和47例间质性膀胱炎病例。NHS II组间质性膀胱炎的患病率为67/100，000，NHS I组为52/100，000。有没有实质性的变化，患病率的年龄。结论：间质性膀胱炎的患病率在美国是超过50%以上，比以前报道的3倍以上，在欧洲报道。
Purpose: Interstitial cystitis is a chronic and debilitating syndrome but surprisingly little is known about its epidemiology. This study was designed to estimate the prevalence of interstitial cystitis among women in the United States.Materials and Methods: Female participants in the Nurses' Health Study (NHS) I and II (184,583) were asked by mailed questionnaires whether they had ever been diagnosed with interstitial cystitis. We requested and reviewed medical records of women self-reporting interstitial cystitis. The accuracy of self-reports was evaluated using standardized criteria.Results: Among the 93,428 women who responded to the NHS II questionnaire and 91,155 women who responded to the NHS I questionnaire 1,354 (1.4%) and 357 (0.4%), respectively, self-reported interstitial cystitis. Based on medical record review 63 cases of interstitial cystitis were confirmed in NHS II and 47 in NHS I. The prevalence of interstitial cystitis was 67/100,000 women in NHS II and 52/100,000 in NHS I. There was no substantial variation in prevalence by age.Conclusions: The prevalence of interstitial cystitis in the United States is more than 50% greater than previously reported and 3-fold greater than that reported in Europe.