EMBOLIC COMPLICATIONS IN PAROXYSMAL ATRIAL-FIBRILLATION
EMBOLIC COMPLICATIONS IN PAROXYSMAL ATRIAL-FIBRILLATION
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DOI：
10.1161/01.str.17.4.622
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发表时间：
1986-07-01
期刊：
影响因子：
8.3
通讯作者：
GODTFREDSEN, J
中科院分区：
文献类型：
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作者：
PETERSEN, P;GODTFREDSEN, J
分析426例阵发性心房颤动（PAF）患者栓塞并发症的发生率。PAF发作时可见明显的栓子聚集。在141例患者（33.1%）转为慢性房颤（CAF）后，栓塞发生率上升到一个新的水平，比PAF患者的发生率高出数倍。此外，在该组中，在过渡到CAF后的第一年期间观察到明显的栓塞聚集。在此背景下，建议PAF患者可能受益于抗凝血剂治疗，以防止CAF的发展，抗凝剂预防卒中似乎特别适合于近期发作的房颤（AF）。
The incidence of embolic complications among 426 patients with initial paroxysmal atrial fibrillation (PAF) was analysed. A distinct clustering of emboli was seen at the time of onset of PAF. After transition to chronic atrial fibrillation (CAF), which developed in 141 patients (33.1%), the incidence of emboli was seen to rise to a new level several times higher than the incidence level for patients with PAF. Also in this group a distinct clustering of emboli was seen during the first year after transition to CAF. On this background it is suggested that patients with PAF may benefit from treatment with antiarrhythmic agents in order to prevent the development of CAF and that anticoagulants for stroke prevention seems especially desirable in atrial fibrillation (AF) of recent onset.