The dorsal anterior cingulate cortex is selective for pain: Results from large-scale reverse inference
The dorsal anterior cingulate cortex is selective for pain: Results from large-scale reverse inference
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DOI：
10.1073/pnas.1515083112
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发表时间：
2015-12-08
影响因子：
11.1
通讯作者：
Eisenberger, Naomi I.
中科院分区：
文献类型：
--
作者：
Lieberman, Matthew D.;Eisenberger, Naomi I.
背侧前扣带回皮质(DACC)的激活常见于疼痛、执行控制、冲突监测和突显加工的研究中，这使得解释dACC的特定心理功能变得困难。使用自动脑图数据库NeuroSynth[包含10,000多项功能磁共振(FMRI)研究]，我们进行了定量的反向推理分析，以探索dACC功能P(psi过程垂直条dACC活动)的最佳一般心理解释。结果清楚地表明，对dACC功能的最佳心理描述与疼痛处理有关--而不是执行、冲突或突显处理。我们的结论是，身体疼痛可能是dACC监控的更广泛类别的与生存相关的目标的一个实例，而不是更随意的临时目标，后者可能由辅助运动区监控。
Dorsal anterior cingulate cortex (dACC) activation is commonly observed in studies of pain, executive control, conflict monitoring, and salience processing, making it difficult to interpret the dACC's specific psychological function. Using Neurosynth, an automated brainmapping database [of over 10,000 functional MRI (fMRI) studies], we performed quantitative reverse inference analyses to explore the best general psychological account of the dACC function P(psi process vertical bar dACC activity). Results clearly indicated that the best psychological description of dACC function was related to pain processing-not executive, conflict, or salience processing. We conclude by considering that physical pain may be an instance of a broader class of survival-relevant goals monitored by the dACC, in contrast to more arbitrary temporary goals, which may be monitored by the supplementary motor area.