Association between adherence to antiretroviral therapy and human immunodeficiency virus drug resistance

Association between adherence to antiretroviral therapy and human immunodeficiency virus drug resistance
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DOI:
10.1086/378301
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发表时间:
2003-10-15
影响因子:
11.8
通讯作者:
Gallant, JE
Gallant, JE
中科院分区:
医学1区
文献类型:
--
作者:
Sethi, AK;Celentano, DD;Gallant, JE

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不坚持高效抗逆转录病毒疗法(HAART)是人类免疫缺陷病毒(HIV)耐药的一个主要原因;然而,与最大耐药风险相关的不坚持程度尚不清楚。从2000年2月开始,约翰·霍普金斯门诊中心(马里兰州巴尔的摩)的195名接受HAART并携带HIV病毒的患者
Nonadherence to highly active antiretroviral therapy (HAART) is a major cause of human immunodeficiency virus (HIV) drug resistance; however the level of nonadherence associated with the greatest risk of resistance is unknown. Beginning in February 2000, 195 patients at the Johns Hopkins Outpatient Center (Baltimore, MD) who were receiving HAART and who had HIV loads of