Minimal in-school SARS-CoV-2 transmission with strict mitigation protocols at two independent schools in Nashville, TN.
Minimal in-school SARS-CoV-2 transmission with strict mitigation protocols at two independent schools in Nashville, TN.
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田纳西州纳什维尔的两所私立学校通过严格的缓解方案，最大限度地减少了学校内 SARS-CoV-2 的传播。
DOI：
10.1101/2021.11.09.21266140
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发表时间：
2021
期刊：
影响因子：
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通讯作者：
Katz,SophieE
中科院分区：
文献类型：
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作者：
Peetluk,LaurenS;Rebeiro,PeterF;Edwards,KathrynM;Banerjee,Ritu;Mallal,SimonA;Aronoff,DavidM;Lipworth,Loren;Katz,SophieE
背景新冠肺炎疫情极大地影响了学校的运营。为了更好地了解学校在新冠肺炎传播中的作用，我们评估了2020-2021学年田纳西州纳什维尔两所独立学校的感染情况。方法估计每所学校、年龄组和暴露环境中新冠肺炎的累积发病率，并与当地发病率进行比较。结果在1401名在校学生中，报告了98例新冠肺炎病例，累积发病率为7.0%(95%可信区间：5.7~8.5)。大多数病例与家庭传播(58%)或社区传播(31%)有关，少数病例与学校内传播(11%)有关。共隔离学生619人日，相当于5000人日缺课，其中仅5人在隔离期间SARS-CoV-2检测呈阳性(初发率：0.8%，95%CI：0.3，1.9)。学校每周的病例发生率与社区传播无关。结论这些结果表明，当采取严格的缓解措施时，即使在社区传播广泛的时期，新冠肺炎在学校的传播也是最小的。对接触者进行严格隔离可能会导致不必要的缺课，对学校内传播的好处微乎其微。
BACKGROUNDThe COVID-19 pandemic has greatly impacted school operations. To better understand the role of schools in COVID-19 transmission, we evaluated infections at two independent schools in Nashville, TN during the 2020-2021 school year.METHODSThe cumulative incidence of COVID-19 within each school, age group, and exposure setting were estimated and compared to local incidence. Primary attack rates were estimated among students quarantined for in-school close contact.RESULTSAmong 1401 students who attended school during the study period, 98 cases of COVID-19 were reported, corresponding to cumulative incidence of 7.0% (95% confidence interval (CI): 5.7-8.5). Most cases were linked to household (58%) or community (31%) transmission, with few linked to in-school transmission (11%). Overall, 619 students were quarantined, corresponding to >5000 person-days of missed school, among whom only 5 tested positive for SARS-CoV-2 during quarantine (primary attack rate: 0.8%, 95% CI: 0.3, 1.9). Weekly case rates at school were not correlated with community transmission.CONCLUSIONThese results suggest that transmission of COVID-19 in schools is minimal when strict mitigation measures are used, even during periods of extensive community transmission. Strict quarantine of contacts may lead to unnecessary missed school days with minimal benefit to in-school transmission.