OSSIFYING FIBROMYXOID TUMOR OF THE NECK CLINICALLY MIMICKING A PRIMARY NEOPLASM OF THE THYROID-GLAND

OSSIFYING FIBROMYXOID TUMOR OF THE NECK CLINICALLY MIMICKING A PRIMARY NEOPLASM OF THE THYROID-GLAND
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DOI:
10.1016/s0344-0338(11)80924-6
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发表时间:
1995-02-01
影响因子:
2.8
通讯作者:
BEHAM, A
BEHAM, A
中科院分区:
医学4区
文献类型:
--
作者:
LAX, SF;RATSCHEK, M;BEHAM, A

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我们介绍了一名 50 岁男性患者,甲状腺前软组织骨化性纤维粘液样瘤 (OFMT) 浸润甲状腺,同时伴有甲状腺肿复发,甲状腺肿切除术后 20 年。该肿瘤最初分别被误诊为甲状腺癌和恶性神经鞘瘤,其组织学上由典型的实性细胞结构和外围的壳状成熟骨组成。此外,在肿瘤附近的组织中,存在一些带有缝合材料的异物肉芽肿和小的增殖神经,作为先前基质切除术的残留物。我们认为这一发现表明了 OFMT 的神经鞘起源。甲状腺全切除术和局部放疗后 3 年的随访显示患者没有复发和转移性疾病。
We present a 50-year-old male patient with an ossifying fibromyxoid tumour (OFMT) of the prethyroidal soft parts infiltrating the thyroid gland in coincidence with recurrent goitre, 20 years after strumectomy. The tumour, initially misdiagnosed as thyroid carcinoma and malignant schwannoma respectively, was histologically composed of typical solid cell-formations and shelly-like mature bone at the periphery. In addition, in the tissue adjacent to the tumour some foreign body granulomas with suture material and small proliferating nerves were present as a residual of the preceding strumectomy. We regard this finding as an indication of nerve sheat origin of OFMT. Follow up of 3 years after total thyroidectomy and local irradiation shows the patient free of recurrent and metastatic disease.