A survey about irritable bowel syndrome in South Korea - Prevalence and observable organic abnormalities in IBS patients

A survey about irritable bowel syndrome in South Korea - Prevalence and observable organic abnormalities in IBS patients
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DOI:
10.1007/s10620-007-9930-1
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发表时间:
2008-03-01
影响因子:
3.1
通讯作者:
Kim, Young Hwan
Kim, Young Hwan
中科院分区:
医学3区
文献类型:
--
作者:
Park, Kyung Sik;Ahn, Sung Hun;Kim, Young Hwan

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本研究的目的是:(1)评估症状型肠易激综合征(IBS)在韩国成年人中的患病率;(2)评估IBS患者中可发现的几种器官异常;(3)分析影响IBS存在的风险或相关因素。成人健康体检者被要求填写一份问卷。IBS的患病率按罗马II标准计算。通过几项测试,在IBS组中发现了几种器质性异常。通过比较IBS组和正常组进行危险因素分析。根据罗马II标准,IBS患病率为16.8%。黏膜增生、淋巴细胞聚集、嗜酸性粒细胞计数增多是IBS组较常见的光镜表现。女性、IBS自觉、排便不规律是IBS的显著独立危险因素或相关因素。上述几种结肠镜检查结果可能有助于IBS的准确诊断。因此,有必要对这些发现进行更精确和更大的人群研究,以得出明确的结论。
The aims of the present study were: (1) to assess the prevalence of symptom-based irritable bowel syndrome (IBS) in Korean adults, (2) to assess several organic abnormalities which can be found in IBS patients, and (3) to analyze the risk or associated factors that influence the presence of IBS. Adult health examinees were requested to fill out a questionnaire. The prevalence of IBS was calculated using Rome II criteria. Using several tests, several organic abnormalities were identified in the IBS group. Risk factors were analyzed by comparing the IBS and normal groups. The prevalence value for IBS according to Rome II criteria was 16.8%. Mucosal hyperplasia, lymphocyte aggregation, and increased eosinophil counts were relatively common microscopic findings in IBS group. Female gender, self-consciousness of IBS, and irregular defecation were expressed as significantly independent risk or associated factors for IBS. Several colonic microscopic findings mentioned above may be helpful in accurate diagnosis of IBS. Therefore a more-precise and large population study about these findings is necessary to reach a definitive conclusion.