Washout of chronic therapeutic deep brain stimulation increases cortical phase-amplitude coupling.
Washout of chronic therapeutic deep brain stimulation increases cortical phase-amplitude coupling.
复制标题
慢性治疗性深部脑刺激的清除会增加皮质相位-幅度耦合。
DOI：
10.1016/j.parkreldis.2019.08.018
复制
发表时间：
2019
影响因子：
4.1
通讯作者：
Starr,PhilipA
中科院分区：
文献类型：
--
作者：
Rajagopalan,SheilaS;Miller,AndrewM;deHemptinne,Coralie;SanLuciano,Marta;Ostrem,JillL;Starr,PhilipA
侵入性人脑记录显示，急性治疗性脑深部刺激(DBS)会降低皮质同步性，通过将β相与伽马幅度耦合来衡量。在这里，我们通过无创性头皮脑电图显示，慢性DBS的撤退增加了相位-幅度耦合，与对侧僵直的恶化成比例。
Invasive human brain recordings have shown that acute therapeutic deep brain stimulation (DBS) reduces cortical synchronization, measured by coupling of beta phase to gamma amplitude. Here we show by noninvasive scalp electroencephalography that withdrawal of chronic DBS elevates phase-amplitude coupling, in proportion to the worsening of contralateral rigidity.