Use of early-TIPS for high-risk variceal bleeding: Results of a post-RCT surveillance study

Use of early-TIPS for high-risk variceal bleeding: Results of a post-RCT surveillance study
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DOI:
10.1016/j.jhep.2012.08.020
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发表时间:
2013-01-01
影响因子:
25.7
通讯作者:
Bosch, Jaime
Bosch, Jaime
中科院分区:
医学1区
文献类型:
--
作者:
Carlos Garcia-Pagan, Juan;Di Pascoli, Marco;Bosch, Jaime

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背景和目标:在最近的一项针对高风险急性静脉曲张出血患者的随机国际临床试验(RCT)中,早期使用经颈静脉肝内门体分流术(TIPS)与治疗失败和死亡率的显著降低相关。本研究的目的是在RCT研究的同一中心的临床实践中证实这些结果。方法:我们回顾性分析了因急性静脉曲张出血和治疗失败高风险(Child C
Background & Aims: In a recent randomized international clinical trial (RCT) in high-risk cirrhotic patients with acute variceal bleeding, the early use of transjugular intrahepatic portosystemic shunt (TIPS) was associated with marked and significant reductions in both treatment failure and mortality. The aim of this study was to confirm these results in clinical practice in the same centers of the RCT study.Methods: We retrospectively reviewed patients admitted for acute variceal bleeding and high risk of treatment failure (Child C