Performance of real-world functional vision tasks by blind subjects improves after implantation with the Argus® II retinal prosthesis system.
Performance of real-world functional vision tasks by blind subjects improves after implantation with the Argus® II retinal prosthesis system.
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DOI：
10.1111/ceo.12812
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发表时间：
2017-03
影响因子：
4
通讯作者：
Argus® II Study Group
中科院分区：
文献类型：
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作者：
Dagnelie G;Christopher P;Arditi A;da Cruz L;Duncan JL;Ho AC;Olmos de Koo LC;Sahel JA;Stanga PE;Thumann G;Wang Y;Arsiero M;Dorn JD;Greenberg RJ;Argus® II Study Group
本研究的主要目的是测试 Argus II 受试者的三项现实世界功能性视觉任务。该研究被设计为随机和前瞻性的。测试是在各个参与中心的医院/研究实验室环境中进行的。 28 名 Argus II 受试者参与了这项研究，他们全都是深度失明的受试者。受试者接受了三个现实世界功能性视觉任务的测试：袜子分类、人行道跟踪和行走方向辨别任务。对于袜子分类任务，正确百分比是根据受试者在铺有布的桌子和光秃秃的桌子上对袜子进行分类的准确程度来计算的。在人行道跟踪任务中，记录了“出界”计数，表示受试者偏离测试路线的频率。在行走方向辨别任务中，测试对象正确识别测试者穿过其视野的方向的次数。发现袜子分类任务的平均正确百分比 OFF 与 ON 在两种测试条件下显着不同（t 检验，P < 0.01）。在人行道跟踪任务中，受试者在系统开启时的表现明显优于系统关闭时的表现（t 检验，P < 0.05）。在行走方向辨别任务中，27 名受试者中的十八 (18) 名 (67%) 在系统开启时表现高于预期，而 6 名受试者 (22%) 在系统关闭时表现出色。 Argus II 受试者在系统开启时比系统关闭时在所有三项任务上的表现都更好。
The main objective of this study was to test Argus II subjects on three real‐world functional vision tasks. The study was designed to be randomized and prospective. Testing was conducted in a hospital/research laboratory setting at the various participating centres. Twenty eight Argus II subjects, all profoundly blind, participated in this study. Subjects were tested on the three real‐world functional vision tasks: Sock Sorting, Sidewalk Tracking and Walking Direction Discrimination task For the Sock Sorting task, percentage correct was computed based on how accurately subjects sorted the piles on a cloth‐covered table and on a bare table. In the Sidewalk Tracking task, an ‘out of bounds’ count was recorded, signifying how often the subject veered away from the test course. During the Walking Direction Discrimination task, subjects were tested on the number of times they correctly identified the direction of testers walking across their field of view. The mean percentage correct OFF versus ON for the Sock Sorting task was found to be significantly different for both testing conditions (t‐test, P < 0.01). On the Sidewalk Tracking task, subjects performed significantly better with the system ON than they did with the system OFF (t‐test, P < 0.05). Eighteen (18) of 27 subjects (67%) performed above chance with the system ON, and 6 (22%) did so with system OFF on the Walking Direction Discrimination task. Argus II subjects performed better on all three tasks with their systems ON than they did with their systems OFF.