Streptococcus mutans biofilm changes surface-topography of resin composites
Streptococcus mutans biofilm changes surface-topography of resin composites
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DOI：
10.1016/j.dental.2007.08.003
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发表时间：
2008-06-01
期刊：
影响因子：
5
通讯作者：
Weiss, Ervin I.
中科院分区：
文献类型：
--
作者：
Beyth, Nurit;Bahir, Ran;Weiss, Ervin I.
目标.据报道，聚合树脂复合材料和非聚合单体可加速细菌生长。此外，在体内，树脂复合材料比其他修复材料积累更多的牙菌斑。本研究的目的是检验假设细菌复合材料表面相互作用引起的表面形貌的变化。在两个载玻片之间聚合树脂复合材料盘。使变形链球菌细胞与盘接触并在盘上生长1天、1周或1个月。使用原子力显微镜分析圆盘。一个月老化的复合材料试样进行了测定的变化，显微硬度和细菌生长。原子力显微镜分析揭示了均方根（RMS）粗糙度的时间依赖性增加（p < 0.0001）。S.变形菌与老化后的复合材料表面直接接触后生长加速，而显微硬度没有变化。结果表明，S.在树脂复合材料上的变形菌生长增加了表面粗糙度而不影响显微硬度。表面完整性的变化可进一步加速生物膜积累。(C)2007年，牙科材料学院。由爱思唯尔有限公司出版。保留所有权利。
Objectives. Polymerized resin composites and nonpolymerized monomers are reported to accelerate bacterial growth. Furthermore, in vivo, resin composite restorations accumulate more plaque than other restorative materials. The purpose of this study was to test the hypothesis that bacteria-composite surface interaction causes changes in surface-topography.Methods. Resin composite disks were polymerized between two glass slides. Streptococcus mutans cells were brought in contact with and grown on the disks for 1 day, 1 week or 1 month. The disks were analyzed using atomic force microscopy. One-month-aged composite specimens were assayed for changes in micro-hardness and bacterial outgrowth.Results. Atomic force microscopy analysis revealed a time-dependent increase in root mean square (RMS) roughness (p < 0.0001). S. mutans outgrowth was accelerated following direct contact with the surface of aged composites, with no changes in micro-hardness.Significance. Our results show that S. mutans growth on resin composite increases surface roughness without affecting micro-hardness. The change in surface integrity may further accelerate biofilm accumulation. (C) 2007 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.