Airway and blood vessel interaction during lung development
Airway and blood vessel interaction during lung development
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DOI：
10.1046/j.1469-7580.2002.00097.x
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发表时间：
2002-10-01
影响因子：
2.4
通讯作者：
Hislop, AA
中科院分区：
文献类型：
--
作者：
Hislop, AA
在成人肺中，肺动脉沿气道而行，肺静脉虽与动脉分离，但与动脉有相似的分支形态。在胎儿早期发育过程中，气道作为肺血管发育的模板，因为血管是在分支气道周围血管新生形成的。在肺发育后期，毛细血管床对肺泡的形成至关重要。本文综述了正常和异常肺发育中气道和血管相互作用的证据。
In the adult lung the pulmonary arteries run alongside the airways and the pulmonary veins show a similar branching pattern to the arteries, though separated from them. During early fetal development the airways act as a template for pulmonary blood vessel development in that the vessels form by vasculogenesis around the branching airways. in later lung development the capillary bed is essential for alveolar formation. This paper reviews evidence for the interaction of the airways and blood vessels in both normal and abnormal lung development.