Phenotypic assortment in Tetrahymena thermophila: assortment kinetics of antibiotic-resistance markers, tsA, death, and the highly amplified rDNA locus.
Phenotypic assortment in Tetrahymena thermophila: assortment kinetics of antibiotic-resistance markers, tsA, death, and the highly amplified rDNA locus.
复制标题
嗜热四膜虫的表型分类：抗生素抗性标记、tsA、死亡和高度扩增的 rDNA 位点的分类动力学。
DOI：
10.1093/genetics/120.2.389
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发表时间：
1988
期刊：
影响因子：
3.3
通讯作者：
Bruns,PJ
中科院分区：
文献类型：
--
作者：
Merriam,EV;Bruns,PJ
嗜热四膜虫的表型配搭是由大核无丝分裂过程中等位基因的随机分布引起的。分类率取决于输入比和分类单元的数量。确定了抗生素耐药性标记Chx、Mpr和gal的分类，并与45个配对染色体的模型一致。基因tsA（以前的ts-1）显示正常的分类，与以前的报道相反。高度扩增的核糖体位点（rdnA2）的突变似乎只存在45个拷贝。无性系的死亡速率与单个基因的配种速率一致。
Phenotypic assortment in Tetrahymena thermophila results from random distribution of alleles during amitotic division of the macronucleus. The rate of assortment is dependent on input ratio and the number of assorting units. The assortment of the antibiotic resistance markers Chx, Mpr and gal was determined and is consistent for each with the model of 45 assorting chromosomes. The gene tsA (previously ts-1) shows normal assortment, in contrast to previous reports. A mutation in the highly amplified ribosomal locus (rdnA2) assorts as if present at only 45 copies. Death of clones occurred at a rate consistent with assortment for a single gene.