Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy
Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy
复制标题
DOI：
10.1017/s0007114510001315
复制
发表时间：
2010-09-01
影响因子：
3.6
通讯作者：
Merkx, Matthias A. W.
中科院分区：
文献类型：
--
作者：
van den Berg, Manon G. A.;Rasmussen-Conrad, Ellen L.;Merkx, Matthias A. W.
临床研究表明，为了预防接受放射治疗的头颈部癌症患者营养不良，营养干预是必要的。本研究的目的是评估与标准营养护理(SC)相比，由营养师进行个别调整的咨询的价值。2005年至2007年间进行的一项前瞻性研究比较了个人饮食咨询(IDC，最佳能量和蛋白质需求)与肿瘤学护士提供的SC(标准营养咨询)。治疗的终点为治疗前、治疗中和治疗后的体重减轻、体重指数和营养不良(体重下降5%/月)。38名患者被平均分布在两组中。与SC组相比，IDC组治疗2个月后体重减轻显著减少(P=0.03)。IDC患者营养不良随时间延长呈下降趋势，SC患者营养不良呈上升趋势(P=0.02)。因此，与接受放射治疗的头颈癌患者相比，营养师早期和密集的个性化饮食咨询在减少体重减轻和营养不良方面产生了临床上相关的效果。
Clinical research shows that nutritional intervention is necessary to prevent malnutrition in head and neck cancer patients undergoing radiotherapy. The objective of the present study was to assess the value of individually adjusted counselling by a dietitian compared to standard nutritional care (SC). A prospective study, conducted between 2005 and 2007, compared individual dietary counselling (IDC, optimal energy and protein requirement) to SC by an oncology nurse (standard nutritional counselling). Endpoints were weight loss, BMI and malnutrition (5% weight loss/month) before, during and after the treatment. Thirty-eight patients were included evenly distributed over two groups. A significant decrease in weight loss was found 2 months after the treatment (P=0.03) for IDC compared with SC. Malnutrition in patients with IDC decreased over time, while malnutrition increased in patients with SC (P=0.02). Therefore, early and intensive individualised dietary counselling by a dietitian produces clinically relevant effects in terms of decreasing weight loss and malnutrition compared with SC in patients with head and neck cancer undergoing radiotherapy.