Analyzing the Dynamics of Signaling Microclusters

Analyzing the Dynamics of Signaling Microclusters
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分析信号微簇的动态

DOI:
10.1007/978-1-4939-6881-7_4
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发表时间:
2017
期刊:
The Immune Synapse
影响因子:
--
通讯作者:
Saito T.
Saito T.
中科院分区:
--
文献类型:
--
作者:
Hashimoto-Tane A;Yokosuka T;Saito T.

文献摘要

相似文献

T 细胞抗原受体 (TCR) 刺激诱导各种类型信号分子的募集和积累,并形成信号微簇。微簇的动态对于调节 T 细胞激活的质量和数量很重要。我们在这里描述了使用支持的平面双层来分析信号微簇的协议。
T cell antigen receptor (TCR) stimulation induces recruitment and accumulation of various types of signaling molecules and forms signaling microclusters. The dynamics of the microclusters are important for regulating the quality and quantity of T cell activation. We describe here our protocols for analysis of signaling microclusters by using supported planar bilayers.