Delayed termination following pacing induced shifts from monomorphic to polymorphic ventricular tachycardia: implications for antitachycardia pacing.
Delayed termination following pacing induced shifts from monomorphic to polymorphic ventricular tachycardia: implications for antitachycardia pacing.
复制标题
起搏后延迟终止引起从单形性室性心动过速转变为多形性室性心动过速：对抗心动过速起搏的影响。
DOI：
10.1109/iembs.2006.260381
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Kay,MatthewW
中科院分区：
文献类型：
--
作者：
Byrd,IsraelA;Pollard,AndrewE;Kay,MatthewW
Interactions between paced wavefronts and monomorphic ventricular tachycardia (VT) dictate antitachycardia pacing outcomes. Monomorphic VTs were initiated in isolated rabbit hearts (n=6) that were endocardially cryoablated to limit viable tissue to the visible epicardium and the ablated apex served as an anatomic anchor. Preparations were optically mapped during single and dual site pacing at 50% to 90% of VT cycle length with 8 pulses per trial. Of these trials, responses to the 48 single site pulses and to the 172 dual site pulses that captured tissue were analyzed. Overall, we found most pulses reset the VT, and a small number of pulses that abruptly terminated the VT. Of particular interest, we found 12 pulses that shifted the anatomically anchored VT to functionally reentrant wavefronts, and thereby induced polymorphic VT. Delayed termination was observed following 6 of these instances, and the underlying non-sustained polymorphic VT's presented temporal characteristics similar to those presented by delayed termination after antitachycardia pacing in ICD patients
