Cognitive and motor impairments predict functional declines in patients with vascular dementia
Cognitive and motor impairments predict functional declines in patients with vascular dementia
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DOI：
10.1002/gps.539
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发表时间：
2002-02-01
影响因子：
4
通讯作者：
Gordon, N
中科院分区：
文献类型：
--
作者：
Boyle, PA;Cohen, RA;Gordon, N
背景血管性痴呆（VaD）与认知、运动和功能领域的损伤有关。VaD患者表现出不同的认知和运动缺陷，但是，这些障碍和独立生活能力之间的关系仍然不清楚。目的-本研究的目的是调查的贡献，由注意/执行和运动功能的预测的基本和工具的日常生活活动在32例VaD患者。我们假设：（a）运动能力对基本日常生活活动有显著的预测作用，而注意/执行能力对基本日常生活活动无显著的预测作用;（B）运动能力和注意/执行能力对工具性日常生活活动均有显著的预测作用。在基本日常生活活动的差异中占很大比例，运动能力和注意/执行能力对工具性日常生活活动有显著的预测作用。结论注意/执行能力对工具性日常生活活动有显著的预测作用。在VaD患者中，执行和运动障碍可能是功能障碍的特定方面的基础。版权所有（C）2002约翰威利父子有限公司
Background Vascular dementia (VaD) is associated with impairments in cognitive, motor, and functional domains. Patients with VaD display diverse cognitive and motor deficits, however, and relationships between these impairments and independent living abilities remain unclear.Objectives The purpose of the present study was to investigate the contributions made by attentional/executive and motor functions in the prediction of basic and instrumental activities of daily living in 32 patients with VaD. We hypothesized that: (a) motor abilities would emerge as a significant predictor of basic activities of daily living, whereas attentional/executive abilities would not, and (b) both motor and attentional/executive abilities would emerge as significant predictors of instrumental activities of daily living.Results Stepwise regression analyses revealed that motor performance, but not attentional/executive abilities, accounted for a significant proportion of the variance in basic activities of daily living, and that both motor and attentional/executive abilities contributed significantly to the prediction of instrumental activities of daily living.Conclusions These results suggest that attentional/executive and motor impairments may underlie specific aspects of functional disability among patients with VaD. Copyright (C) 2002 John Wiley Sons, Ltd.