Human immune repertoire in hepatitis B virus infection.
Human immune repertoire in hepatitis B virus infection.
复制标题
B型肝炎病毒感染中的人类免疫谱。
DOI:
10.3748/wjg.v27.i25.3790
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发表时间:
2021-07-07
影响因子:
4.3
通讯作者:
Zeng Z
中科院分区:
文献类型:
--
作者:
Zhan Q;Xu JH;Yu YY;Lo Kk E;Felicianna;El-Nezami H;Zeng Z
Hepatitis B virus (HBV) infection is a public health threat that affects 257 million people worldwide and can progress to liver cirrhosis, liver failure, and hepatocellular carcinoma. The HBV antigen- induced adaptive immune response plays an important role in HBV clearance. Immune repertoire sequencing (IRS) has been used to investigate the molecular mechanisms behind the immune system, find novel ways to treat HBV infection, and evaluate the genetic responses and immune characteristics of individuals infected by HBV or immunized by HBV vaccine. This review summarizes the human immune repertoire analysis methodology, and the application of the IRS in the prediction of HBV infection progression, treatment, and vaccination.
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影响因子:
12.3
作者:
Galson JD;Trück J;Clutterbuck EA;Fowler A;Cerundolo V;Pollard AJ;Lunter G;Kelly DF
通讯作者:
Kelly DF
影响因子:
7.3
作者:
Bernat, Nestor Vazquez;Corcoran, Martin;Hedestam, Gunilla B. Karlsson
通讯作者:
Hedestam, Gunilla B. Karlsson
影响因子:
5.5
作者:
Larsen, CE;Xu, JH;Alper, CA
通讯作者:
Alper, CA
影响因子:
7.4
作者:
Yang J;He J;Lu H;Wei L;Li S;Wang B;Diao H;Li L
通讯作者:
Li L
影响因子:
7
作者:
Freeman, J. Douglas;Warren, Rene L.;Holt, Robert A.
通讯作者:
Holt, Robert A.